Osteoconductive Scaffold

Opus™ is a synthetic osteoconductive scaffold that is compression resistant, fully resorbable, and easily customizable for a range of clinical applications.


  • Comprised of Carbonate Apatite Bone Mineral and Type 1 Collagen
    • Carbonate Apatite Bone Mineral has similar porosity and resorption as human bone1,2
    • Type 1 Collagen is a great wicking material, binds proteins and cells, and retains biological factors3
  • Easily hydrated and compression resistant
  • Available in multiple configurations and sizes


Opus, combined with autogenous bone marrow, is intended for use in filling bony voids or gaps of the skeletal system (i.e., the extremities, spine and pelvis) that are not intrinsic to the stability of the bony structure. These defects may be surgically created osseous defects or osseous defects resulting from traumatic injury to the bone.


  1. Matsuura, A., Kubo, T., Doi K., Hayashi, K., Morita, K., Yokota, R., Hayashi, H., Hirata, I., Okazaki, M., Akagawa, Y. (2009). Bone formation ability of carbonate apatite-collagen scaffolds with different carbonate contents. Dental Materials Journal, 28(2), 234-242.
  2. Ellies, LG., Carter, J.M., Natiella, J.R., Featherstone, J.D.B., Nelson, D.G.A. (1988). Quantitative analysis of early in vivo tissue response to synthetic apatite implants. J. of Biomed. Mater. Res., 22, 137-148.
  3. Geiger, M., Li, R.H., Friess, W. (2003). Collagen sponges for bone regeneration with rhBMP-2. Science Direct / Elsevier, 55, 1613-1629. http://doi.org/10.1016/j.addr.2003.08.010

Opus is manufactured by Collagen Matrix, Inc.